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Two-Tier Lyme Disease Serology Test Results Can...

Variability in 2-tier Lyme disease test results according to the specific first-tier enzyme immunoassay (EIA) in children has not been examined rigorously. In this study, investigators paired results of clinical 2-tier Lyme disease tests to …MORE

A minority of children diagnosed with Lyme dise...

Of 1770 children undergoing emergency department evaluation for Lyme disease, 362 (20.5%) children had Lyme disease. Of those with an available tick bite history, only a minority of those with Lyme disease had a recognized …MORE

Evaluation of the Modified Two-Tiered Testing M...

Conventional two-tiered testing (CTTT) for Lyme disease includes a first-tier enzyme immunoassay (EIA) followed by a supplemental immunoblot, and modified two-tiered testing (MTTT) relies on two different sequential EIAs without the inclusion of an immunoblot. …MORE

The Lyme Disease Polymerase Chain Reaction Test...

The Lyme PCR is a direct detection test, but has not been rigorously evaluated in children undergoing evaluation for acute Lyme disease. Published in Vector-Borne and Zoonotic Diseases: https://www.liebertpub.com/doi/10.1089/vbz.2019.2547 PubMed: https://www.ncbi.nlm.nih.gov/pubmed/31821110

Diagnostic Performance of C6 Enzyme Immunoassay...

In Lyme disease endemic areas, initial management of children with arthritis can be challenging because diagnostic tests take several days to return results, leading to potentially unnecessary invasive procedures. Our objective was to examine the …MORE

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