In this article, the authors used a mouse model to study B cells, which when activated, produce antibodies and release inflammatory cytokines, or chemical messengers. They found that a protein called CLIP is important in controlling B cells, and speculated that it shows a potential pathway to control chronic immune activation diseases such as Crohn’s disease and post-treatment Lyme disease.
TLR-mediated B cell activation results in ectopic CLIP expression that promotes B cell-dependent inflammation.
by Admin at Global Lyme Alliance on February 19, 2010